The Kores Group
Pharmaceutical & Chemical Division
CIN: U21198MH1936PLC002494

Reaction Capabilities

1. CHLORINATION :

  • Nuclear chlorination with Chlorine gas.
  • Nuclear chlorination with Sulphuryl chloride.

6. REDUCTION :

  • Ester, ketone, aldehyde reductions with borohydride.
  • Nitroso reduction with iron / acid and polysulphide.
  • Imine reduction with borohydride.
  • Oxime reduction with metal acid.
  • Catalytic hydrogenation using Pdlc.

2. ALCOHOL TO CHLORIDES :

  • With Thionyl chloride.
  • With Hydrochloric acid

7. OXIDATION :

  • Alcohols to aldehydes under
    controlled condition.

3. BROMINATION :

  • Nuclear bromination with Liquid bromine.
  • Side chain bromination with N-Bromosuccinimide.

8. AMIDATION :

  • Acid / Ester to amides.
  • Amine formylation

4. CYANATION :

  • Halide replacement with cyanide using Sodium cyanide.

9. HETEROCYCLE SYNTHESIS :

  • Oxazoles
  • Purines / Xanthines
  • Pyrimidines
  • Benzisoxazoles
  • Oxadiazoles
  • Benzothiazoles

5. ALKYLATION :

  • N-Alkylation with dialkyl sulphate and alkyl halides.
  • O-Alkylation with dialkyl sulphate and alkyl halides.
  • S-Alkylation with alkyl halides.
  • C-Alkylation with dialkyl sulphate and alkyl halides.

10. MALONIC ESTER SYNTHESIS

11. WITTIG AND RELATED REACTIONS

12. PHASE TRANSFER CATALYST + SYNTHESIS AND REACTIONS

13. QUARTERNARY HYDROXIDE SYNTHESIS

14. FISCHER OXAZOLE SYNTHESIS

15. GRIGNARD

16. VILSEMEIER HAACK

17. HYDROGENATION

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