1. CHLORINATION :
- Nuclear chlorination with Chlorine gas.
- Nuclear chlorination with Sulphuryl chloride.
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6. REDUCTION :
- Ester, ketone, aldehyde reductions with borohydride.
- Nitroso reduction with iron / acid and polysulphide.
- Imine reduction with borohydride.
- Oxime reduction with metal acid.
- Catalytic hydrogenation using Pdlc.
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2. ALCOHOL TO CHLORIDES :
- With Thionyl chloride.
- With Hydrochloric acid
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7. OXIDATION :
- Alcohols to aldehydes under
controlled condition.
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3. BROMINATION :
- Nuclear bromination with Liquid bromine.
- Side chain bromination with N-Bromosuccinimide.
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8. AMIDATION :
- Acid / Ester to amides.
- Amine formylation
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4. CYANATION :
- Halide replacement with cyanide using Sodium cyanide.
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9. HETEROCYCLE SYNTHESIS :
- Oxazoles
- Purines / Xanthines
- Pyrimidines
- Benzisoxazoles
- Oxadiazoles
- Benzothiazoles
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5. ALKYLATION :
- N-Alkylation with dialkyl sulphate and alkyl halides.
- O-Alkylation with dialkyl sulphate and alkyl halides.
- S-Alkylation with alkyl halides.
- C-Alkylation with dialkyl sulphate and alkyl halides.
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10. MALONIC ESTER SYNTHESIS
11. WITTIG AND RELATED REACTIONS
12. PHASE TRANSFER CATALYST + SYNTHESIS AND REACTIONS
13. QUARTERNARY HYDROXIDE SYNTHESIS
14. FISCHER OXAZOLE SYNTHESIS
15. GRIGNARD
16. VILSEMEIER HAACK
17. HYDROGENATION
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